October 1, 2002

10:41 AM

"...the drug aroused female rodents 'so quickly they started mounting males.'" The new Viagra? Or Spanish Fly that works? Could lawsuits ensue? ("I only thought I consented--but he had somehow slipped me some Nasal Spray PT-141.") ...the company hopes to market PT-141 for humans in two or three years... [to] people with sexual problems...
posted by Shane (50 comments total)

"The crucial point about PT-141 is that it directly targets the brain's arousal centre," said Dr Carl Spana...
(as opposed to having a physical effect on the body such as increased circulation.)

This just isn't what is meant by the saying, "the brain is the largest sexual organ." Once again, Science nudges Nature out of the way...

"Maybe, when they find out more about chemicals," he said, "there won't have to be policemen or wars or crazy houses or divorces or drunks or juvenile delinquents or women gone bad or anything any more."

"That sure would be nice," I said.

"It's possible," he said.

"I believe you," I said.

And yet another moral occurs to me now: Make love when you can. It's good for you.

Mother Night, Vonnegut (1961)

When I get depressed, I take a little pill, and I cheer up again.

Breakfast of Champions, Vonnegut
posted by Shane at 10:44 AM on October 1, 2002

Given that more than 40 per cent of women suffer from 'female sexual dysfunction' - they are interested in sex but cannot reach climax...

Jesus, it's not the females with the disfunction... It's the men they are with who can't get them off.

A spray, or pill, or whatever, is not going to change that. Men need to be more sexually considerate, and women need to encourage that behavior in men.

'Nuff said.
posted by eas98 at 10:52 AM on October 1, 2002

Will this be available in one of those cute 'plug-ins' room spray things?
posted by HTuttle at 10:52 AM on October 1, 2002

...room spray things?
LOL, Buttle! I mean, 'Tuttle.'
posted by Shane at 10:56 AM on October 1, 2002

HT: More likely, it will be available as a cologne for men.
posted by mischief at 10:59 AM on October 1, 2002

"Do I really love him or is it just his Eau de PT-149? How can I tell?"

Maybe all men will need PT-149 to level the playing field. Picture the marketing. Of course, it's only for "people with sexual problems," just like Viagra...
posted by Shane at 11:05 AM on October 1, 2002

I prefer PT-73: The musky scent of Ernest Borgnine.
posted by Kafkaesque at 11:07 AM on October 1, 2002

...the company hopes to market PT-141 for humans in two or three years... [to] people with sexual problems...

It seems to me that if you take this drug you WILL have sexual problems.
posted by blue_beetle at 11:08 AM on October 1, 2002

Pig spittle
posted by inpHilltr8r at 11:18 AM on October 1, 2002

One must catch said pussy before one can eat it.
posted by mischief at 11:26 AM on October 1, 2002

'The drug can only be administered as a nasal spray - which isn't good for seducers. You can't put it in a drink and sticking it up a girl's nose is hard to do surreptitiously, after all"

Well, I know what cocaine is going to have in it in a couple of years.

In the article they mention that it would be for men, too, but it doesn't look like they done any sort of experiments with me. How do they know it will help impotence?
posted by witchstone at 11:28 AM on October 1, 2002

It's the men they are with who can't get them off.

You might be surprised to learn that you're wrong. There does exist such a thing as female sexual dysfunction, and it isn't necessarily caused by unskilled men.

Enough with your silly generalizations. Though it may be difficult for you to accept, some women simply cannot have an orgasm.
posted by rocketman at 11:29 AM on October 1, 2002

Shit. The last half of that sentence should say "it doesn't look like they've done any sort of experiments with men."

Obviously they've already done experiments with me, so that's a moot point.
posted by witchstone at 11:30 AM on October 1, 2002

Was there a cockroach control group wearing little cockroach glasses?

I feel like all I ever post is smartass quips.
posted by stupidsexyFlanders at 11:33 AM on October 1, 2002

You might be surprised to learn that you're wrong. There does exist such a thing as female sexual dysfunction, and it isn't necessarily caused by unskilled men.

Sure, but "more than 40 per cent" of women?

I'll go with luriete's solution.
posted by goethean at 11:42 AM on October 1, 2002

oops. first line was quoted. meant to italicize.
posted by goethean at 11:42 AM on October 1, 2002

Pig spittle
Um, musk lollies?
I feel like all I ever post is smartass quips
This begs for smartass quips.
"PT-141: Cheaper than a sports car."
"Grass is faster... well, not anymore..."
"What does that guy have that I don't? Oh, yeah: PT-141..."
posted by Shane at 11:44 AM on October 1, 2002

Its been my experience that the unskilled problem lies in the fact that men believe that the female gentalia work in the same way as the male genitalia... NOT!

But I go with luriete's solution...
posted by SweetIceT at 11:50 AM on October 1, 2002

Hey, am I the only one who saw the first line and wondered (and am still wondering) "how did the female mice go about mounting the males?"

I mean, it's not like they do it face to face usually. Did the females make an exception in this case? Did they willfully back into the males? Did they have tiny mouse-sized strap-ons or something? What?
posted by soyjoy at 11:52 AM on October 1, 2002

witchstone: Well, I know what cocaine is going to have in it in a couple of years.

Any guy who can get a girl to snort cocaine with him, and still needs to add an aphrodesiac to the cocaine to get her interested, is a guy with a much more serious problem.
posted by bingo at 11:55 AM on October 1, 2002

I have a feeling a lot of perverted psychos are going to make cocaine look like Pixy Stix.

perverted psychos : cocaine :: cocaine : Pixy Stix?

So, okay, you don't take Pixy Stix nasally, whereas you do take cocaine that way. So, X is to nasally as nasally is to orally, and where X is an attribute of perverted psychos.

My brain hurts.
posted by kindall at 12:16 PM on October 1, 2002

Perhaps KWYJIBO's problem is that he *has* been taking Pixy Stix nasally...
posted by Danelope at 12:32 PM on October 1, 2002

/me spikes the Afrin
posted by MCBenC at 12:45 PM on October 1, 2002

but "more than 40 per cent" of women?

I have no comment on their statistics. There are some women who cannot reach an orgasm even through oral sex.

What surprises me is the arrogance of men who believe that they hold the answer to a woman's sexual frustration; that regardless of her individual anatomy, they are "the chosen one" to bring her to orgasm.

Sorry guys, but there are women you cannot please, no matter your educated technique.
posted by rocketman at 12:54 PM on October 1, 2002

Although I would hastily add that I have a healthy respect for your attitude.

A man really should want to bring a woman to climax. All I'm saying is there are some cases where it can't be done.
posted by rocketman at 1:00 PM on October 1, 2002

PT-109 sure did a lot for John Kennedy's sex life.
posted by briank at 1:06 PM on October 1, 2002

You guys make me laugh. I wish all men cared so much about getting their partners off. As my friend said the other day after having sex with a guy she picked up: "How a guy can be 24 and still be that bad at sex is just a crime. It's pathetic."

This isn't going to make sex any better. It will just make women want it more. Guys, you still have to do your part!

(BTW: Bad luriete! No gift on the anniversary! All the mouth in the world isn't going to make up for that screw up!)
posted by aacheson at 1:15 PM on October 1, 2002

Needs graphics:

I prefer PT-73: The musky scent of Ernest Borgnine.
PT-109 sure did a lot for John Kennedy 's sex life.
posted by Shane at 1:15 PM on October 1, 2002

some women simply cannot have an orgasm.
posted by inpHilltr8r at 1:20 PM on October 1, 2002

I actually read once that only 25% of women can orgasm vaginally during sex. I don't know if that's completely accurate, but it's a pretty high number either way.

Not being an expert by any means (any ladies can fill me in if they'd like), I've always thought part of the problem for at least some of the women who can't orgasm at all--even clitorally from oral sex--is mental. Perhaps they're uncomfortable with the situation for whatever reason and can't relax enough to enjoy it. I know a large part of sexuality is mental for women, which is why they enjoy written erotica more than their visually-driven male counterparts.
posted by The God Complex at 1:23 PM on October 1, 2002

I actually read once that only 25% of women can orgasm vaginally during sex.

I've often read similar stats, or stats giving much higher percentages, but when I ask my (platonic, married) women friends about it, they all say, "Nope." "Not me." "No problemo."

So either the stats are BS, or I'm not as close to my women friends as I thought.
posted by kirkaracha at 1:30 PM on October 1, 2002

and to be fair about all this, its not completely up to the male. its not like the woman is an instrument to get to sing. it's a work-together thing.

however, if the woman chooses to be the instrument that i can play, i have no problem with that whatsoever. its just that it doesnt have to be that way, by default.
posted by oog at 2:22 PM on October 1, 2002

And unfortunate side effect to the new drig is the patient's strong desire to eat cheese, gnaw on their cage, and spread the bubonic plague.
posted by crunchland at 2:26 PM on October 1, 2002

And unfortunate side effect to the new drig is the patient's strong desire to eat cheese, gnaw on their cage, and spread the bubonic plague.

It turns women into Rosie O'Donnell?
posted by Danelope at 2:43 PM on October 1, 2002

I've often read similar stats, or stats giving much higher percentages, but when I ask my (platonic, married) women friends about it, they all say, "Nope." "Not me." "No problemo."

I've always seen this sort of number in statistics which listed vaginal stimulation and clitoral stimulation as separate things. It makes a big difference, I suspect.
posted by atbash at 3:07 PM on October 1, 2002

That's what I was talking about, atbash. My comment about clitoral stimulation was sort of leading down a different road (talking about the mental aspect of an orgasm).
posted by The God Complex at 4:31 PM on October 1, 2002

A doctor friend of mine told me that vaginal orgasms are actually inadvertent clitoral orgasms brought on by indirect stimulation of the clitoris during intercourse. But what does he know? He doesn't have a vagina or a clitoris.
posted by Devils Slide at 4:33 PM on October 1, 2002

Vaginal orgasms, my ass. There aint no such thing (and, being a women, we do discuss such things.) So guys, all those p0rn videos where the women "comes" when absolutly NOTHING is happening to her clitoris, it just ain't true. And if some woman says she did and nothing was happening there, she's lyin to you.
posted by aacheson at 4:52 PM on October 1, 2002

>Vaginal orgasms, my ass. There aint no such thing (and, being a women, we do discuss such things.) So guys, all those p0rn videos where the women "comes" when absolutly NOTHING is happening to her clitoris, it just ain't true. And if some woman says she did and nothing was happening there, she's lyin to you.

Quite a few women, with no reason to stroke my ego, have told me otherwise.
posted by McBain at 5:35 PM on October 1, 2002

Sixteen healthy women were given the drug and 16 were given a placebo. All were shown erotic videos, while detectors measured blood flow in their vaginas.

Wow, how do I get a job hooking up vaginal blood flow detectors? Suddenly I regret not paying more attention in biology class.
posted by RylandDotNet at 6:03 PM on October 1, 2002

To paraphrase.. and caused the aroused females to mount the males. Somewhat what happened here.

So it appears that PT-141 is a peptide, which would explain why it is administered nasally instead of orally. Reports indicate that it targets a melanocortin receptor, hardly a unique enterprise in the industry.

Just more hype from a biotech going down the tubes.
posted by paleocon at 6:58 PM on October 1, 2002

Vaginal orgasms, my ass. There aint no such thing...

Is too.

"how did the female mice go about mounting the males?"

I think you're confusing "mounting" (the act of climbing onto another animal's back, usually for the purpose of mating, but also to display dominance and for other forms of communication) with "mating" (actually engaging in intercourse). The female mice could mount mice of either sex, no problem, mating is a whole other thing.
posted by biscotti at 7:07 PM on October 1, 2002

Scientists last week revealed they had successfully tested a nasal spray, PT-141, that sent 'healthy, normal women' into states of high sexual arousal.


Around here I get PT-141 action by burying my nose in my lover's sweaty armpit...

And luriete: that polite term is "licking the kitty".
posted by Secret Life of Gravy at 7:31 PM on October 1, 2002

...the company hopes to market PT-141 for humans in two or three years... [to] people with sexual problems...

Great. Now I can anticipate the spam that will be showing up in my inbox three years from now.
posted by pmurray63 at 8:21 PM on October 1, 2002

stupidsexyflanders: you also make them in the wrong thread, the glasses thread was thatta way

;-)
posted by Ynoxas at 8:27 PM on October 1, 2002

"It's made from monkey cum!"
posted by tpoh.org at 8:32 PM on October 1, 2002

Vaginal orgasms, my ass.

That's an interesting trick

There aint no such thing

Either I'm a freak or that's rubbish.
posted by Summer at 3:40 AM on October 2, 2002

I say bring it on! Imagine how many relationships this could save.
posted by plasticbaby at 4:49 AM on October 2, 2002

I'm not a woman, but I've been with some very selfish, sexually demanding women who made their own orgasm a high priority (and I don't blame them), who claimed to find satisfaction without clitoral stimulation. They were very specific about stating what they wanted, how they wanted it, and when they'd gotten it, and if they were making it all up, I can't imagine their motivation for doing so.
posted by bingo at 11:45 AM on October 2, 2002

So guys, all those p0rn videos where the women "comes" when absolutly NOTHING is happening to her clitoris, it just ain't true. And if some woman says she did and nothing was happening there, she's lyin to you.- aacheson

Some women can orgasm without ever manually stimulating themselves. Also, 90% of the Sudanse women interviewed reported orgasms, despite the fact they had had their clitoris removed. Hanny Lightfoot-Klein (1989) Journal of Sex Research v. 26, p 375-392, did the research, because I know you're not going to believe me. The brain is a very powerful sexual tool.
posted by stoneegg21 at 11:19 AM on October 5, 2002